TEST CATALOG ORDERING & RESULTS SPECIMEN HANDLING CUSTOMER SERVICE EDUCATION & INSIGHTS
Test Catalog

Test ID: FMONP    
Motor Neuropathy Panel

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Asialo-GM1 Antibodies, IgG/IgM

29 IV or less: Negative

30-50 IV: Equivocal

51-100 IV: Positive

101 IV or greater: Strong Positive

 

GM1 Antibodies, IgG/IgM

29 IV or less: Negative

30-50 IV: Equivocal

51-100 IV: Positive

101 IV or greater: Strong Positive

 

GD1a Antibodies, IgG/IgM

29 IV or less: Negative

30-50 IV: Equivocal

51-100 IV: Positive

101 IV or greater: Strong Positive

 

GD1b Antibodies, IgG/IgM

29 IV or less: Negative

30-50 IV: Equivocal

51-100 IV: Positive

101 IV or greater: Strong Positive

 

GQ1b Antibodies, IgG/IgM

29 IV or less: Negative

30-50 IV: Equivocal

51-100 IV: Positive

101 IV or greater: Strong Positive

 

Ganglioside (Asialo-GM1, GM1, GM2, GD1a, GD1b, and GQ1b) Antibodies, IgG/IgM:

 

Ganglioside antibodies are associated with diverse peripheral neuropathies. Elevated antibody levels to ganglioside-monosialic acid (GM1), and the neutral glycolipid, asialo GM1 are associated with motor or sensorimotor neuropathies, particularly multifocal motor neuropathy. Anti-GM1 may occur as IgM (polyclonal or monoclonal) or IgG antibodies. These antibodies may also be found in patients with diverse connective tissue diseases as well as normal individuals. GD1a antibodies are associated with different variants of Guillain-Barre syndrome (GBS) particularly acute motor axonal neuropathy while GD1b antibodies are predominantly found in sensory ataxic neuropathy syndrome. Anti-GQ1b antibodies are seen in more than 80 percent of patents with Miller-Fisher syndrome and may be elevated in GBS patients with ophthalmoplegia. The role of isolated anti-GM2 antibodies is unknown. These tests by themselves are not diagnostic and should be used in conjunction with other clinical parameters to confirm disease.  

 

Total Protein, Serum

6.00-8.30 g/dL

 

Albumin

3.75-5.01 g/dL

 

Alpha-1 Globulins

0.19-0.46 g/dL

 

Alpha-2 Globulins

0.48-1.05 g/dL

 

Beta Globulins

0.48-1.10 g/dL

 

Gamma

0.62-1.51 g/dL

 

Immunoglobulin A

0 – 30 days:

1 – 7 mg/dL

9 – 11 months:

16 – 83 mg/dL

1 month:

1 – 53 mg/dL

1 year:

14 – 105 mg/dL

2 months:

3 – 47 mg/dL

2 years:

14 – 122 mg/dL

3 months:

5 – 46 mg/dL

3 years:

22 – 157 mg/dL

4 months:

4 – 72 mg/dL

4 years:

25 – 152 mg/dL

5 months:

8 – 83 mg/dL

5 - 7 years:

33 – 300 mg/dL

6 months:

8 – 67 mg/dL

8 – 9 years:

45 – 234 mg/dL

7 – 8 months:

11 – 89 mg/dL

10 years and older:

68 – 408 mg/dL

 

Immunoglobulin G

 0 – 30 days:

611 – 1542 mg/dL

9 – 11 months:

282 – 1026 mg/dL

1 month:

241 – 870 mg/dL

1 year:

331 – 1164 mg/dL

2 months:

198 – 577 mg/dL

2 years:

407 – 1009 mg/dL

3 months:

169 – 558 mg/dL

3 years:

423 – 1090 mg/dL

4 months:

188 – 536 mg/dL

4 years:

444 – 1187 mg/dL

5 months:

165 – 781 mg/dL

5 – 7 years:

608 – 1229 mg/dL

6 months:

206 – 676 mg/dL

8 – 9 years:

584 – 1509 mg/dL

7 – 8 months:

208 – 868 mg/dL

10 years and older:

768 – 1632 mg/dL

 

Immunoglobulin M

0 – 30 days:

0 – 24 mg/dL

9 – 11 months:

39 – 142 mg/dL

1 month:

19 – 83 mg/dL

1 year:

41 – 164 mg/dL

2 months:

16 – 100 mg/dL

2 years:

46 – 160 mg/dL

3 months:

23 – 85 mg/dL

3 years:

45 – 190 mg/dL

4 months:

26 – 96 mg/dL

4 years:

41 – 186 mg/dL

5 months:

31 – 103 mg/dL

5 – 7 years:

46 – 197 mg/dL

6 months:

33 – 97 mg/dL

8 – 9 years:

49 – 230 mg/dL

7 – 8 months:

32 – 120 mg/dL

10 years and older:

35 – 263 mg/dL

 

Myelin Associated Glycoprotein (MAG) Antibody, IgM

Less than 1000 TU

 

An elevated IgM antibody concentration greater than 999 TU against myelin-associated glycoprotein (MAG) suggests active demyelination in peripheral neuropathy. A normal concentration (less than 999 TU) generally rules out an anti-MAG antibody-associated peripheral neuropathy.

TU= Titer Units

 

Sulfate-3 Glucuronyl Paragloboside (SGPG) Antibody, IgM

Less than 1.00 IV